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Chlorite (sodium salt) Quickview (CASRN 7758-19-2)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Chlorite (sodium salt)

File First On-Line: 11/01/1995; Last Significant Revision: 10/11/2000

Category (section)
Last Revised
Oral RfD Assessment Yes 10/12/2000
Inhalation RfC Assessment Discussion 10/12/2000
Carcinogenicity Assessment Yes 10/12/2000
  • 14998-27-7
  • Chlorite
  • Chlorous acid, ion (1-)
  • Clorito [Spanish]
  • Chlorite (sodium salt)
Chlorite (sodium salt) Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Neurodevelopmental effects NOAEL : 3 mg/kg-day 100 3 x10-2 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Information reviewed but value not estimated. See IRIS Summary.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
    • Carcinogenic potential cannot be determined
  • Weight-of-Evidence Narrative:
    • Under the current guidelines (U.S. EPA, 1986), chlorite is classified as Group D; not classifiable as to human carcinogenicity because of inadequate data in humans and animals. Under the draft Carcinogen Assessment Guidelines (U.S. EPA, 1996), the human carcinogenicity of chlorite cannot be determined because of a lack of human data and limitations in animal studies.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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