Jump to main content.

1,2-Epoxybutane (EBU) Quickview (CASRN 106-88-7)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for 1,2-Epoxybutane (EBU)

File First On-Line: 05/01/1992; Last Significant Revision: 05/01/1992

Category (section)
Last Revised
Oral RfD Assessment No
Inhalation RfC Assessment Yes 05/01/1992
Carcinogenicity Assessment No
  • 106-88-7
  • 1,2-Epoxybutane
  • Butane, 1,2-epoxy-
  • Butylene oxide
  • Bthylethylene oxide
  • n-Butene-1,2-oxide
  • 1-Butene oxide
  • 1-Butylene oxide
  • 1,2-Butene oxide
  • 1,2-Butylene oxide
  • 2-Ethyloxirane
  • Epoxybutane (EBU)
1,2-Epoxybutane (EBU) Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advirsories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

Top of page

Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
Degenerative lesions of the nasal cavity LOAEL (HEC): 4.8 mg/m3 300 2x10-2 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

Top of page

Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

Top of page

Recent Additions | Advanced Search | IRIS Home | Environmental Assessment | Research

Local Navigation

Jump to main content.