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1,2-Dichloropropane Quickview (CASRN 78-87-5)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for 1,2-Dichloropropane

File First On-Line: 12/01/1991; Last Significant Revision: 12/01/1991

Category (section)
Status
Last Revised
Oral RfD Assessment No data
Inhalation RfC Assessment On-line 12/01/1991
Carcinogenicity Assessment No data
Synonyms
  • 78-87-5
  • Propane, 1,2-dichloro-
  • Propylene dichloride
  • 1,2-Dichloropropane
  • AI3-15406
  • alpha,beta-Dichloropropane
  • alpha,beta-Propylene dichloride
  • Bichlorure de propylene [French]
  • Caswell No. 324
  • CCRIS 951
  • Dichloro-1,2 propane [French]
  • more...
1,2-Dichloropropane Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
UF RfC
Hyperplasia of the nasal mucosa LOAEL (HEC): 1.3 mg/m3 300 4x10-3 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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