Jump to main content.


n-Hexane Quickview (CASRN 110-54-3)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for n-Hexane

File First On-Line: 07/01/1990; Last Significant Revision: 12/23/2005

Category (section)
Status
Last Revised
Oral RfD Assessment Discussion 12/23/2005
Inhalation RfC Assessment On-line 12/23/2005
Carcinogenicity Assessment Discussion 12/23/2005
Synonyms
  • 110-54-3
  • n-Hexane
  • Hexyl hydride
  • NCI-C60571
  • Skellysolve B
n-Hexane Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

Top of page


Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
UF RfC
Peripheral neuropathy (decreased MCV at 12 weeks) BMCL (HEC): 215 mg/m3 300 7x10-1 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

Top of page

Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • Inadequate information to assess carcinogenic potential
  • Weight-of-Evidence Narrative:
    • Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005b), there is inadequate information to assess the carcinogenic potential of n-hexane.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

Top of page


Recent Additions | Advanced Search | IRIS Home | Environmental Assessment | Research


Local Navigation


Jump to main content.