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Aramite Quickview (CASRN 140-57-8)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Aramite

File First On-Line: 06/01/1991; Last Significant Revision: 06/01/1991

Category (section)
Last Revised
Oral RfD Assessment No
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 06/01/1991
  • 140-57-8
  • Sulfurous acid, 2-(p-t-butylphenoxy)-1-methylethyl-2-chloroethyl ester
  • Sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester
  • Sulfurous acid, 2-chloroethyl 2-(4-(1,1-dimethylethyl)phenoxy)-1-methylethyl ester
  • 2-p-tert-Butylphenoxyisopropyl 2-chloroethyl sulfite
  • Acaracide
  • AI3-16519
  • Aracide
  • Aramit
  • Aramite
  • Aramite-15W
  • more...
Aramite Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals)
  • Weight-of-Evidence Narrative:
    • Based on no human data and sufficient data from animal bioassays including increased incidence of liver tumors and/or neoplastic nodules in three strains of male and female rats and males of one strain of mice, and extrahepatic biliary system tumors in dogs following chronic oral exposure.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

Oral Slope Factor(s)
Extrapolation Method
2.5 x10-2 per mg/kg-day Linearized multistage procedure, extra risk
Drinking Water Unit Risks
7.1x10-7 per µg/L
Risk Level
E-4 (1 in 10,000) 1x102 µg/L
E-5 (1 in 100,000) 1x101 µg/L
E-6 (1 in 1,000,000) 1 µg/L

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

Inhalation Unit Risk(s)
Extrapolation Method
7.1 x10-6 per µg/m3 Linearized multistage procedure, extra risk

Inhalation Concentrations at Specified Risk Levels

Risk Level
E-4 (1 in 10,000) 1x101 µg/m3
E-5 (1 in 100,000) 1 µg/m3
E-6 (1 in 1,000,000) 1x10-1 µg/m3

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