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Selenium and Compounds Quickview (CASRN 7782-49-2)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Selenium and Compounds

File First On-Line: 03/01/1991; Last Significant Revision: 06/01/1991

Category (section)
Last Revised
Oral RfD Assessment Yes 06/01/1991
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 03/01/1991
  • 7782-49-2
  • Selenium
  • Caswell No. 732
  • Elemental Selenium
  • HSDB 4493
  • Selen [polish]
  • Selenio [Spanish]
  • Selenium
  • Selenium alloy
  • Selenium base
  • Selenium dust
  • more...
Selenium and Compounds Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, Supplementary Data were removed from IRIS on or before April, 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Clinical selenosis NOAEL : 1.5 x10-2 mg/kg-day 3 5 x10-3 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
  • Weight-of-Evidence Narrative:
    • Based on inadequate human data and inadequate evidence of carcinogenicity in animals. The evidence for various selenium compounds in animal and mutagenicity studies is conflicting and difficult to interpret; however, evidence for selenium sulfide is sufficient for a B2 (probable human carcinogen) classification.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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