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Indeno[1,2,3-cd]pyrene Quickview (CASRN 193-39-5)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Indeno[1,2,3-cd]pyrene

File First On-Line: 12/01/1990; Last Significant Revision: 03/01/1994

Category (section)
Status
Last Revised
Oral RfD Assessment No data
Inhalation RfC Assessment No data
Carcinogenicity Assessment On-line 03/01/1994
Synonyms
  • 2,3-Phenylenepyrene
  • 193-39-5
  • HSDB 5101
  • Indeno(1,2,3-cd)pyrene
  • RCRA Waste Number U137
  • 1,10-(o-Phenylene)pyrene
  • 2,3-o-Phenylenepyrene
  • Indeno[1,2,3-cd]pyrene
  • Indeno(1,2,3-cd)pyrene
  • o-Phenylenepyrene
  • 1,10-(1,2-Phenylene)pyrene
Indeno[1,2,3-cd]pyrene Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals)
  • Weight-of-Evidence Narrative:
    • Based on no human data and sufficient data from animal bioassays. Indeno[1,2,3-cd]pyrene produced tumors in mice following lung implants, subcutaneous injection and dermal exposure. Indeno[1,2,3-cd]pyrene tested positive in bacterial gene mutation assays.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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