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1,2-Dichlorobenzene Quickview (CASRN 95-50-1)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for 1,2-Dichlorobenzene

File First On-Line: 08/01/1989; Last Significant Revision: 11/01/1990

Category (section)
Last Revised
Oral RfD Assessment Yes 08/01/1989
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 11/01/1990
  • 95-50-1
  • Benzene, 1,2-dichloro-
  • Benzene, o-dichloro-
  • Chloroben
  • Chloroden
  • Cloroben
  • DCB
  • o-Dichlorbenzene
  • o-Dichlor benzol
  • o-Dichlorobenzene
  • 1,2-Dichlorobenzene
  • more...
1,2-Dichlorobenzene Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
No adverse effects observed NOAEL : 8.57 x101 mg/kg-day 1000 9 x10-2 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
  • Weight-of-Evidence Narrative:
    • Based on no human data and evidence of both negative and positive trends for carcinogenic responses in rats and mice.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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