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Hydrogen chloride Quickview (CASRN 7647-01-0)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Hydrogen chloride

File First On-Line: 06/01/1989; Last Significant Revision: 07/01/1995

Category (section)
Last Revised
Oral RfD Assessment No
Inhalation RfC Assessment Yes 07/01/1995
Carcinogenicity Assessment No
  • 7647-01-0
  • acide chlorhydrique (french)
  • acido cloridrico (italian) 362
  • chloorwaterstof (dutch)
  • chlorohydric acid
  • chlorowodor (polish)
  • chlorwasserstoff (german)
  • hydrochloric acid
  • hydrochloride
  • hydrogen chloride
  • muriatic acid
  • more...
Hydrogen chloride Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
Hyperplasia of nasal mucosa larynx and trachea LOAEL (HEC): 6.1 mg/m3 300 2x10-2 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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