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Coke oven emissions Quickview (CASRN 8007-45-2)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Coke oven emissions

File First On-Line: 05/01/1989; Last Significant Revision: 01/01/1991

Category (section)
Status
Last Revised
Oral RfD Assessment No data
Inhalation RfC Assessment No data
Carcinogenicity Assessment On-line 03/01/1994
Synonyms
  • 8007-45-2
  • Coke oven emissions
  • Coal tar pitch volatiles, as benzene soluble organics
Coke oven emissions Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • A (Human carcinogen)
  • Weight-of-Evidence Narrative:
    • Studies of coke oven workers have shown increased risk of mortality from cancer of the lung, trachea and bronchus; cancer of the kidney; cancer of the prostate; and cancer at all sites combined. In animals, extracts and condensates of coke oven emissions were found to be carcinogenic in both inhalation studies and skin-painting bioassays. The mutagenicity of whole extracts and condensates, as well as their individual components, provides supportive evidence for carcinogenicity.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

Inhalation Unit Risk(s)
Extrapolation Method
6.2 x10-4 per µg/m3 Linearized multistage procedure

Inhalation Concentrations at Specified Risk Levels

Risk Level
Concentration
E-4 (1 in 10,000) 2x10-1 µg/m3
E-5 (1 in 100,000) 2x10-2 µg/m3
E-6 (1 in 1,000,000) 2x10-3 µg/m3

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