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Napropamide Quickview (CASRN 15299-99-7)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Napropamide

File First On-Line: 07/01/1989; Last Significant Revision: 07/01/1989

Category (section)
Last Revised
Oral RfD Assessment Yes 07/01/1989
Inhalation RfC Assessment No
Carcinogenicity Assessment No
  • 15299-99-7
  • devrinol
  • n,n-Diethyl-2-(1-naphthalenyloxy)propionamide
  • n,n-Diethyl-2-(1-naphthyloxy)propionamide
  • 2-(alpha-Naphthoxy)-n,n-diaethyl-propionsaeureamid (german)
  • 2-(alpha-Naphthoxy)-n,n-diethylpropionamide
  • Napropamide
  • Propionamide, n,n-diethyl-2-(1-naphthyloxy)-
  • R-7465
  • R-7475
Napropamide Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Decreased body weight gain in parental animals and pups NOEL : 3.0 x101 mg/kg-day 300 1 x10-1 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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