Jump to main content.

Isoxaben Quickview (CASRN 82558-50-7)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Isoxaben

File First On-Line: 09/26/1988; Last Significant Revision: 09/01/1991

Category (section)
Last Revised
Oral RfD Assessment Yes 09/26/1988
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 09/01/1991
  • 82558-50-7
  • Caswell No. 419f
  • Compound 121607
  • EL-107
  • EPA Pesticide Chemical Code 125851
  • Isoxaben
  • n-(3-(1-Ethyl-1-methylpropyl)isoxazol-5-yl)-2,6-dimethoxybenzamide
  • n-(3-(1-Ethyl-methylpropyl)-5-isoxazolyl)-2,6-dimethoxybenzamide
  • n-(3-(1-Ethyl-1-methylpropyl)-5-isoxazolyl)-2,6-dimethoxybenzamide (9ci)
  • Benzamide, n-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)-2,6-dimethoxy-
Isoxaben Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Increased BUN; decreased serum AP and AST; decreased food consumption efficiency; increased heart/body weight NOEL : 5 mg/kg-day 100 5 x10-2 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

Top of page

Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

Top of page

Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • C (Possible human carcinogen)
  • Weight-of-Evidence Narrative:
    • Based on a statistically significant increased incidence of benign liver tumors in one species.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

Top of page

Recent Additions | Advanced Search | IRIS Home | Environmental Assessment | Research

Local Navigation

Jump to main content.