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Hexachlorophene Quickview (CASRN 70-30-4)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Hexachlorophene

File First On-Line: 08/22/1988; Last Significant Revision: 08/22/1988

Category (section)
Last Revised
Oral RfD Assessment On-line 04/01/1991
Inhalation RfC Assessment No data
Carcinogenicity Assessment No data
  • 70-30-4
  • Almederm
  • AT-17
  • Bilevon
  • bis-2,3,5-Trichlor-6-hydroxyfenylmethan
  • bis(3,5,6-Trichloro-2-hydroxyphenyl)methane
  • Cotofilm
  • Dermadex
  • 2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane
  • 2,2'-Dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane
  • Exofene
  • more...
Hexachlorophene Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Swollen salivary glands, status spongiosis in brain and optic nerve LEL : 7.5 x10-1 mg/kg-day 3000 3 x10-4 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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