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2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP) Quickview (CASRN 93-72-1)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for 2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP)

File First On-Line: 08/22/1988; Last Significant Revision: 09/07/1988

Category (section)
Last Revised
Oral RfD Assessment Yes 09/07/1988
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 08/22/1988
  • 2 (2,4,5-Trichlorophenoxy) propionic acid
  • 93-72-1
  • Acide 2-(2,4,5-trichloro-phenoxy) propionique
  • Acido 2-(2,4,5-tricloro-fenossi)-propionico
  • alpha-(2,4,5-Trichlorophenoxy)propionic acid
  • Propanoic acid, 2-(2,4,5-trichlorophenoxy)-
  • Propionic acid, 2-(2,4,5-trichlorophenoxy)-
  • Silvex
  • 2,4,5-Tp
  • 2-(2,4,5-Trichloor-fenoxy)-propionzuur
  • 2,4,5-Trichlorophenoxy-alpha-propionic acid
  • more...
2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP) Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Histopathological changes in liver NOEL : 7.5 x10-1 mg/kg-day 100 8 x10-3 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
  • Weight-of-Evidence Narrative:
    • Human data are not available and the available animal cancer bioassay studies are considered to be inadequate.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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