Jump to main content.

Acetaldehyde Quickview (CASRN 75-07-0)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Acetaldehyde

File First On-Line: 06/30/1988; Last Significant Revision: 10/01/1991

Category (section)
Last Revised
Oral RfD Assessment No data
Inhalation RfC Assessment On-line 10/01/1991
Carcinogenicity Assessment On-line 01/01/1991
Under Re-Assessment
  • Acetaldehyd
  • Acetaldehyde
  • Acetylaldehyde
  • Aldehyde acetique
  • Ethanal
  • Ethyl aldehyde
  • NCI-C56326
  • RCRA Waste Number u001
  • UN 1089
  • 75-07-0
  • Acetic aldehyde
  • more...
Acetaldehyde Source Documents
Revision History
Date Section Description
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

Top of page

Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
Degeneration of olfactory epithelium NOAEL (HEC): 8.7 mg/m3 1000 9x10-3 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

Top of page

Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals)
  • Weight-of-Evidence Narrative:
    • Based on increased incidence of nasal tumors in male and female rats and laryngeal tumors in male and female hamsters after inhalation exposure.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

Inhalation Unit Risk(s)
Extrapolation Method
2.2 x10-6 per µg/m3 Linearized multistage-variable exposure input form (extra risk)

Inhalation Concentrations at Specified Risk Levels

Risk Level
E-4 (1 in 10,000) 5x101 µg/m3
E-5 (1 in 100,000) 5 µg/m3
E-6 (1 in 1,000,000) 5x10-1 µg/m3

Top of page

Recent Additions | Advanced Search | IRIS Home | Environmental Assessment | Research

Local Navigation

Jump to main content.