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Lactofen Quickview (CASRN 77501-63-4)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Lactofen

File First On-Line: 06/30/1988; Last Significant Revision: 06/30/1988

Category (section)
Last Revised
Oral RfD Assessment Yes 06/30/1988
Inhalation RfC Assessment No
Carcinogenicity Assessment No
  • 77501-63-4
  • Benzoic acid, 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitro-,2-ethoxy-1-methyl-2-oxoethyl ester, (+-)- (9ci)
  • Cobra
  • Cobra [herbicide]
  • (+-)-2-Ethoxy-1-methyl-2-oxoethyl 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2 nitrobenzoate
  • Lactofen
  • Lactofen [ANSI]
  • PPG 844
  • Benzoic acid, 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitro-,2-ethoxy-1-methyl-2-oxoethyl ester
Lactofen Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Increased absolute and relative liver weight; hepatocytomegaly in males LEL : 1.5 mg/kg-day 1000 2 x10-3 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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