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Pentabromodiphenyl ether Quickview (CASRN 32534-81-9)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Pentabromodiphenyl ether

File First On-Line: 03/31/1987; Last Significant Revision: 08/01/1990

Category (section)
Last Revised
Oral RfD Assessment Yes 03/31/1987
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 08/01/1990
  • 32534-81-9
  • Benzene, 1,1'-oxybis-, pentabromo deriv.
  • DE 71
  • Pentabromodiphenyl ether
Pentabromodiphenyl ether Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Induction of hepatic enzymes NOAEL : 1.77 mg/kg-day 1000 2 x10-3 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
  • Weight-of-Evidence Narrative:
    • No human data and animal data available.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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