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Fosetyl-al Quickview (CASRN 39148-24-8)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Fosetyl-al

File First On-Line: 03/31/1987; Last Significant Revision: 08/22/1988

Category (section)
Last Revised
Oral RfD Assessment Yes 03/31/1987
Inhalation RfC Assessment No
Carcinogenicity Assessment Yes 08/22/1988
  • 32545 RP
  • 39148-24-8
  • Aliette
  • Aluminum tris(o-ethyl phosphonate)
  • Epal
  • Fosetyl-al
  • Phosethyl
  • Phosphonic acid, monoethyl ester, aluminum salt
  • Efosite-al
  • LS 74783
  • Phosethyl al
Fosetyl-al Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Slight testicular degeneration NOEL : 2.50 x102 mg/kg-day 100 3 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • C (Possible human carcinogen)
  • Weight-of-Evidence Narrative:
    • Increased incidence of urinary bladder tumors (adenomas/carcinomas combined) in male rats. No increase in tumor incidence occurred in female rats or in mice of either sex.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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