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Bentazon (Basagran) Quickview (CASRN 25057-89-0)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Bentazon (Basagran)

File First On-Line: 03/03/1987; Last Significant Revision: 03/02/1998

Category (section)
Status
Last Revised
Oral RfD Assessment On-line 03/02/1998
Inhalation RfC Assessment No data
Carcinogenicity Assessment On-line 03/02/1998
Synonyms
  • 25057-89-0
  • BAS 351-H
  • Basagran
  • Bendioxide
  • Bentazon
  • Bentazone
  • 1 h-2,1,3-Benzothiadiazin-4 (3h)-one-2,2-dioxide, 3-isopropyl-
  • 3-Isopropyl-2,1,3-benzothiadiazinon-(4)-2,2-dioxid
  • 3-Isopropyl-1 h-2, 1-3-benzothiadiazin-4(3h)-one-2,2-dioxide
  • 3-(1-Methylethyl)-1h-2,1,3-benzothiazain-4(3h)-one,2,2-dioxide
  • Bentazon (Basagran)
Bentazon (Basagran) Source Documents
Revision History
Date Section Description
03/02/1998 I.A., II., VI. New RfD, cancer assessment
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
UF RfD
Blood loss into the gastrointestinal tract; coagulation defect in male and female dogs (other effect: Dose-related increase in red areas (presumed blood) in feces; coagulation defect. ) NOAEL (ADJ): 3.2 mg/kg-day 100 3.0 x10-2 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • E (Evidence of non-carcinogenicity for humans)
    • Not likely to be carcinogenic to humans
  • Weight-of-Evidence Narrative:
    • Under EPA's 1986 Guidelines for Carcinogen Risk Assessment, Bentazon would be classified as evidence of non-carcinogenicity for humans, or a Group E chemical. Under EPA's proposed guidelines for carcinogen risk assessment (U.S. EPA, 1996), Bentazon would be characterized as not likely to be carcinogenic to humans by any route of exposure.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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