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Pentachlorobenzene Quickview (CASRN 608-93-5)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Pentachlorobenzene

File First On-Line: 01/31/1987; Last Significant Revision: 11/01/1992

Category (section)
Status
Last Revised
Oral RfD Assessment On-line 03/01/1988
Inhalation RfC Assessment No data
Carcinogenicity Assessment On-line 02/01/1995
Synonyms
  • 608-93-5
  • Pentachlorobenzene
  • RCRA Waste Number U183
  • QCB
  • Benzene, pentachloro-
Pentachlorobenzene Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
UF RfD
Liver and kidney toxicity LOAEL : 8.3 mg/kg-day 10000 8 x10-4 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
  • Weight-of-Evidence Narrative:
    • No human data and no animal data available.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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