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Hydrogen sulfide Quickview (CASRN 7783-06-4)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Hydrogen sulfide

File First On-Line: 01/31/1987; Last Significant Revision: 07/28/2003

Category (section)
Last Revised
Oral RfD Assessment Withdrawn; discussion 07/28/2003
Inhalation RfC Assessment Yes 07/28/2003
Carcinogenicity Assessment Yes 07/28/2003
  • 7783-06-4
  • Dihydrogen monosulfide
  • Dihydrogen sulfide
  • Hydrogen sulfide
  • Hydrogen sulphide
  • Hydrosulfuric acid
  • Sulfureted hydrogen
  • Sulfur hydride
  • Acide sulfhydrique [French]
  • Acide sulphhydrique
  • EINECS 231-977-3
  • more...
Hydrogen sulfide Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Information reviewed but value not estimated. See IRIS Summary.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
Nasal lesions of the olfactory mucosa NOAEL (HEC): 0.64 mg/m3 300 2x10-3 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • Data are inadequate for an assessment of human carcinogenic potential
  • Weight-of-Evidence Narrative:
    • Under the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999), data are inadequate for an assessment of the carcinogenic potential of hydrogen sulfide.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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