Jump to main content.

Hexachlorobutadiene Quickview (CASRN 87-68-3)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Hexachlorobutadiene

File First On-Line: 01/31/1987; Last Significant Revision: 05/01/1993

Category (section)
Last Revised
Oral RfD Assessment Withdrawn 05/01/1993
Inhalation RfC Assessment No data
Carcinogenicity Assessment On-line 04/01/1991
Under Re-Assessment
  • 87-68-3
  • 1,3-Butadiene, hexachloro-
  • Dolen-pur
  • GP-40-66:120
  • HCBD
  • Hexachlor-1,3-butadien
  • Hexachlorbutadiene
  • Hexachlorobutadiene
  • 1,1,2,3,4,4-Hexachloro-1,3-butadiene
  • 1,3- Hexachlorobutadiene
  • Perchlorobutadiene
  • more...
Hexachlorobutadiene Source Documents
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Information reviewed but value not estimated. See IRIS Summary.

Top of page

Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

Top of page

Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • C (Possible human carcinogen)
  • Weight-of-Evidence Narrative:
    • Observation of renal neoplasms in male and female rats in one study.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

Oral Slope Factor(s)
Extrapolation Method
7.8 x10-2 per mg/kg-day Linearized multistage procedure, extra risk
Drinking Water Unit Risks
2.2x10-6 per µg/L
Risk Level
E-4 (1 in 10,000) 5x101 µg/L
E-5 (1 in 100,000) 5 µg/L
E-6 (1 in 1,000,000) 5x10-1 µg/L

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

Inhalation Unit Risk(s)
Extrapolation Method
2.2 x10-5 per µg/m3 Linearized multistage procedure, extra risk

Inhalation Concentrations at Specified Risk Levels

Risk Level
E-4 (1 in 10,000) 5 µg/m3
E-5 (1 in 100,000) 5x10-1 µg/m3
E-6 (1 in 1,000,000) 5x10-2 µg/m3

Top of page

Recent Additions | Advanced Search | IRIS Home | Environmental Assessment | Research

Local Navigation

Jump to main content.