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Ethylbenzene Quickview (CASRN 100-41-4)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Ethylbenzene

File First On-Line: 01/31/1987; Last Significant Revision: 03/01/1991

Category (section)
Status
Last Revised
Oral RfD Assessment On-line 06/01/1991
Inhalation RfC Assessment On-line 03/01/1991
Carcinogenicity Assessment On-line 08/01/1991
Under Re-Assessment
Synonyms
  • Benzene, ethyl
  • EB
  • Ethylbenzeen
  • Ethylbenzol
  • Etilbenzene
  • Phenylethane
  • UN 1175
  • Aethylbenzol
  • Ethylbenzene
  • Etylobenzen
  • NCI-C56393
  • 100-41-4
Ethylbenzene Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advirsories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
UF RfD
Liver and kidney toxicity NOEL : 9.71 x101 mg/kg-day 1000 1 x10-1 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
UF RfC
Developmental toxicity NOAEL (HEC): 4.34 x102 mg/m3 300 1 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
  • Weight-of-Evidence Narrative:
    • Nonclassifiable due to lack of animal bioassays and human studies.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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