Jump to main content.


Barium and Compounds Quickview (CASRN 7440-39-3)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Barium and Compounds

File First On-Line: 01/31/1987; Last Significant Revision: 07/11/2005

Category (section)
Status
Last Revised
Oral RfD Assessment On-line 07/11/2005
Inhalation RfC Assessment On-line 03/30/1998
Carcinogenicity Assessment On-line 03/30/1998
Synonyms
  • 7440-39-3
  • Barium
  • UN 1399
  • UN 1400
  • UN 1854
  • Barium and Compounds
Barium and Compounds Source Documents
Revision History
Date Section Description
01/21/1999 I.A. Minor revisions to RfD Assessment, revised critical effect
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
UF RfD
Nephropathy BMDL05 : 63 mg/kg-day 300 0.2 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

Top of page


Reference Concentration for Chronic Inhalation Exposure (RfC)

Information reviewed but value not estimated. See IRIS Summary.

Top of page

Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • D (Not classifiable as to human carcinogenicity)
    • Carcinogenic potential cannot be determined (Inhalation route)
    • Not likely to be carcinogenic to humans (Oral route)
  • Weight-of-Evidence Narrative:
    • Under EPA's 1986 Guidelines for Carcinogen Risk Assessment, barium would be classified as Group D, not classifiable as to human carcinogenicity. Under the Proposed Guidelines for Carcinogenic Risk Assessment (U.S. EPA, 1996), barium is considered not likely to be carcinogenic to humans following oral exposure and its carcinogenic potential cannot be determined following inhalation exposure.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

Top of page


Recent Additions | Advanced Search | IRIS Home | Environmental Assessment | Research


Local Navigation


Jump to main content.