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63885 
Journal Article 
Aspects of the toxicology of chloroprene: Immediate and long-term effects 
Sanotskii, IV 
1976 
Yes 
Environmental Health Perspectives
ISSN: 0091-6765
EISSN: 1552-9924 
17 
OCT 
85-93 
English 
799963 
WOS:A1976DP11000012 
The maximum permissible concentration (MPC) of chloroprene was set at 2 mg/m3 in the USSR in the 1940's. The existing MPC is 4 mg/m3. The threshold of systemic effects as a result of chronic chloroprene exposure is l.69 mg/m3. However, the threshold for embryotoxic and mutagenic effects is 0.15 mg/m3. In consideration of this information, setting a new MPC for chloroprene at 0.05 mg/m3 is recommended. 
Adult; Animals; Blood Cell Count; Butadienes/adverse effects/analogs & derivatives/toxicity; Central Nervous System/drug effects; Chemical Industry; Embryo, Mammalian/drug effects; Hemodynamics/drug effects; Maximum Allowable Concentration; Mice, Inbred C57BL; Middle Aged; Mutagens; Occupational Diseases/chemically induced; Pregnancy; Spermatogenesis/drug effects; Time Factors; Vestibular Function Tests 
IRIS
• Chloroprene
     Cited 2009 Draft
     Cited 2010 Final
• Formaldehyde
     Reproductive and Developmental Effects
          Cited
               Animal
     Retroactive RIS import
          2015
               FA DevRepro 072115
                    Abstract/Full Text Screen
                         Animal-In Document