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HERO ID
68186
Reference Type
Journal Article
Subtype
Review
Title
Review of epidemiologic studies of paternal occupational exposure and spontaneous abortion
Author(s)
Savitz, DA; Sonnenfeld, NL; Olshan, AF
Year
1994
Is Peer Reviewed?
Yes
Journal
American Journal of Industrial Medicine
ISSN:
0271-3586
EISSN:
1097-0274
Volume
25
Issue
3
Page Numbers
361-383
Language
English
PMID
8160656
Abstract
The question of whether paternal exposures influence risk of spontaneous abortion is of great public interest, with the possibility supported by laboratory investigations. Thirty-nine studies of male occupational exposure and risk of spontaneous abortion were examined, with the methods and results tabulated. Many of those reports were limited by exposure data based on maternal report of the father's job title or by potentially inaccurate paternal reports of spontaneous abortion, though the quality of more recent studies is markedly enhanced. Mercury has been implicated most strongly based on recent studies that included quantitative exposure estimates; a number of studies showing associations for exposure to anesthetic gases. Suggestive associations have also been found inconsistently for exposure to lead, rubber manufacturing, selected solvents, and some pesticides. Further study is encouraged, but with more intensive effort to measure accurately both spontaneous abortion and occupational exposures.
Tags
IRIS
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Chloroprene
Cited 2009 Draft
Cited 2010 Final
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