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HERO ID
667208
Reference Type
Book/Book Chapter
Title
Draft revised guideline 203: Fish, acute toxicity test
Author(s)
Organisation for Economic Co-operation and Development :: OECD
Year
1992
Publisher
OECD Publishing
Book Title
OECD Guideling for testing of chemicals
URL
http://www.oecd.org/dataoecd/45/30/41888165.pdf
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Abstract
OECD Guidelines for Testing of Chemicals are periodically reviewed to ensure that they reflect the best available science. In the revision of this Guideline (originally adopted in 1981, updated in 1984 and 1992), special attention was given to possible improvements in relation to animal welfare concerns in order to avoid unnecessary testing in laboratory animals. According to this updated version of Guideline 203, prior to undertaking the described fish acute toxicity test it should be evaluated whether the Threshold Approach provided as Annex 2 to this guideline is applicable. The Threshold Approach takes into consideration EC50 values from relevant algae and acute invertebrate (e.g. daphnia) tests.
Retrieval Date
11/17/2010
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