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62914 
Journal Article 
Mortality follow-up of workers exposed to 1,4-dioxane 
Buffler, PA; Wood, SM; Suarez, L; Kilian, DJ 
1978 
Yes 
Journal of Occupational and Environmental Medicine
ISSN: 1076-2752
EISSN: 1536-5948 
20 
255-259 
English 
641607 
As a result of recent interest in the carcinogenic effect of dioxane, a mortality study was conducted on employees exposed to this compound at a major chemical company plant. Standard follow-up techniques were used to ascertain the vital status of a total of 165 employees ever exposed to dioxane since 1954. Observed deaths from overall cancer were not significantly different from the expected number of deaths. The observations were based on small numbers of deaths of employees who were apparently exposed at low levels and for relatively short exposures. 
Dioxanes; Dioxins; Dioxanes/poisoning; Dioxins/poisoning; Environmental Exposure; Follow-Up Studies; Middle Aged; Neoplasms/chemically induced; Occupational Diseases/mortality; Time Factors 
IRIS
• 1,4-Dioxane - with inhalation update
     Final (2013)
     External Review Draft (2011)
OPPT REs
• OPPT_1,4-Dioxane_C. Engineering
     Data screening total
          Screening: Included
     Data evaluation total
          Evaluation: Acceptable
• OPPT_1,4-Dioxane_D. Exposure
     Total – title/abstract screening
          Off topic
          Supplemental Search
               Consumer Use
• OPPT_1,4-Dioxane_E. Fate
     Total – title/abstract screening
          Off topic
• OPPT_1,4-Dioxane_F. Human Health
     Total – title/abstract screening
          On topic
               Peer review
                    Primary source
               Cited in IRIS document or IRIS HERO page
     On topic - additional tags for titles/abstracts
          Human hazard ID