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Citation
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HERO ID
157560
Reference Type
Journal Article
Title
Categorization framework to aid exposure assessment of nanomaterials in consumer products
Author(s)
Hansen, SF; Michelson, ES; Kamper, A; Borling, P; Stuer-Lauridsen, F; Baun, A
Year
2008
Is Peer Reviewed?
Yes
Journal
Ecotoxicology
ISSN:
0963-9292
EISSN:
1573-3017
Volume
17
Issue
5
Page Numbers
438-447
Language
English
PMID
18454314
DOI
10.1007/s10646-008-0210-4
Web of Science Id
WOS:000256314700010
Abstract
Exposure assessment is crucial for risk assessment for nanomaterials. We propose a framework to aid exposure assessment in consumer products. We determined the location of the nanomaterials and the chemical identify of the 580 products listed in the inventory maintained by the Woodrow Wilson International Center for Scholars, of which 37% used nanoparticles suspended in liquids, whereas <1% contained "free airborne nanoparticles". C(60) is currently only used as suspended nanoparticles in liquids and nanosilver is used more as surface bound nanoparticles than as particles suspended in liquids. Based on the location of the nanostructure we were able to further group the products into categories of: (1) expected, (2) possible, and (3) no expected exposure. Most products fall into the category of expected exposure, but we were not able to complete a quantitative exposure assessment mainly due to the lack of information on the concentration of the nanomaterial in the products--a problem that regulators and industry will have to address if we are to have realistic exposure assessment in the future. To illustrate the workability of our procedure, we applied it to four product scenarios using the best estimates available and/or worst-case assumptions. Using the best estimates available and/or worst-case assumptions we estimated the consumer exposure to be 26, 15, and 44 microg kg(-1) bw year(-1) for a facial lotion, a fluid product, and a spray product containing nanoparticles, respectively. The application of sun lotion containing 2% nanoparticles result in an exposure of 56.7 mg kg(-1) bw d(-1) for a 2-year-old child, if the amounts applied correspond to the European Commission recommendations on use of sunscreen.
Keywords
nanomaterials; categorization; exposure assessment; consumer products
Tags
•
Nanoscale Silver
External Review Draft
Final Case Study
Exposure, Uptake and Dose
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