IRIS Toxicological Review of Methanol (Interagency Science Consultation Draft)
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On January 12, 2010, the Toxicological Review of Methanol and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Methanol and the charge to external peer reviewers are posted on this site.
|Sep 1988||EPA posted the assessment of an oral reference dose for methanol on the IRIS Database.|
|Jul 1993||EPA revised the oral reference dose for methanol.|
|May 2002||EPA started draft development of an IRIS reassessment of methanol.|
|Jun 2009||An external peer review of unpublished New Energy Development Organization (NEDO) studies (for a 24-month rat study and an 18-month mouse study) was completed.|
|Dec 2009||EPA hosted an interagency science consultation on the draft IRIS Toxicological Review of Methanol for cancer and non-cancer health effects.|
|Jan 2010||EPA released the IRIS Toxicological Review of Methanol (External Review Draft) on cancer and non-cancer health effects for public review and comment, and announced the public listening session would be held on February 23, 2010. [Federal Register Jan 12, 2010]|
|Jun 2010||Following a report from the National Toxicology Program, EPA placed on hold the draft Methanol Toxicological Review on cancer and non-cancer health effects (see June 15, 2010 press release).|
|Apr 2011||EPA released the IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft) for public review and comment. EPA also announced a public listening session to be held on May 26, 2011 in Arlington, VA. [Federal Register Apr 18, 2011]|