IRIS Toxicological Review and Summary Documents for 1,1,1-Trichloroethane (External Review Draft)
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EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,1-trichloroethane that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization.
The assessment of 1,1,1-trichloroethane is one of the chemicals in a pilot to explore the inclusion of reference values for less-than-lifetime exposure and other health assessment procedures/features recommended in the Risk Assessment Forum’s 2002 report, A Review of the Reference Dose and Reference Concentration Processes.
|1987||IRIS assessment of 1,1,1-trichloroethane posted on the IRIS database. (RfD only)|
|1988||Carcinogenicity assessment for 1,1,1-trichloroethane added to the IRIS database. [Related link]|
|1991||RfD withdrawn from the IRIS database.|
|Feb 2007||EPA released the external review draft for public review and comment.|
|Apr 2007||EPA hosted an independent peer review panel workshop to discuss the draft report.|
|Sep 2007||EPA released the final Toxicological Review of 1,1,1-Trichloroethane: in support of the Integrated Risk Information System (IRIS).|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- (187 pp, 2 MB, about PDF)