IRIS Toxicological Review of Inorganic Arsenic (Cancer) (Interagency Science Consultation Draft)
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On February 19, 2010, the draft IRIS Toxicological Review of Inorganic Arsenic (Cancer) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the Toxicological Review of Inorganic Arsenic and the charge to external peer reviewers are posted on this site.
|1999||NRC reviews the 1988 IRIS assessment and the available health data for inorganic arsenic and makes recommendations for updating the cancer assessment.|
|2001||NRC updated the NRC (1999) report and evaluated the toxicological risk and health effects of arsenic as relevant to the 2001 Arsenic Rule.|
|2001||NRC reviews the 2001 Primary Drinking Water Standard for inorganic Arsenic and EPA’s supporting risk assessment and makes recommendations for applying epidemiologic data in the cancer health assessment.|
|2003||EPA started a reassessment of the IRIS assessment for inorganic arsenic.|
|Jul 2005||EPA submitted the 2005 EPA reassessment of cancer assessment for inorganic arsenic to EPA’s Science Advisory Board (SAB) for review.|
|Jun 2007||SAB posted the 2007 SAB Response to the 2005 EPA reassessment of inorganic arsenic (cancer). [Link to the SAB Report and Review Panel Meetings]|
|Oct 2008||The draft IRIS Toxicological Review for Inorganic Arsenic (cancer) was submitted to OMB for interagency review.|
|Feb 2010||EPA released the draft IRIS Toxicological Review for Inorganic Arsenic (cancer) to SAB and simultaneously to the public for review and comment, focusing on EPA’s responses to the SAB (2007) report.|