Health and Environmental Effects Profile for Toluidines
The Health and Environmental Effects Profile for Toluidines was prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste to support listings of hazardous constituents of a wide range of waste streams under Section 3001 of the Resource Conservation and Recovery Act (RCRA). Both published literature and information obtained from Agency program office files were evaluated as they pertained to potential human health, aquatic life and environmental effects of hazardous waste constituents. Quantitative estimates have been presented provided sufficient data are available. o-Toluidine and p-toluidine have been evaluated as carcinogens. The human carcinogen potency factor (q1*) for o-Toluidine is .24 per (mg/kg bw/day) and for p-toluidine is .19 per (mg/kg bw/day) for oral exposure. Quantitative estimates have been presented provided sufficient data are available. Existing data are insufficient to determine an Acceptable Daily Intake (ADI) or a carcinogenic potency factor for m-toluidine.