Provisional Peer-Reviewed Toxicity Values for Pyrene

Provisional Peer-Reviewed Toxicity Value (PPRTV) assessments support the EPA mission to protect human health and the environment by identifying and characterizing the health hazards of chemicals of concern to the Superfund and RCRA Programs, and providing an important source of toxicity information and toxicity values for such chemicals. PPRTVs [provisional oral reference doses (p-RfDs), inhalation reference concentrations (p-RfCs), cancer risk values, and screening values] are derived after a review of the relevant scientific literature and using Agency methodologies, practices, and guidance for the development of toxicity values. Other EPA programs or external parties who choose of their own initiative to use PPRTV values are advised that Superfund resources will not be used to respond to challenges of these PPRTVs used in a context outside of the EPA Superfund Program.

Citation

U.S. EPA. Provisional Peer-Reviewed Toxicity Values for Pyrene. U.S. Environmental Protection Agency, Washington, DC, EPA/690/R-07/032F, 2007.

History/Chronology

Date Description
01-Sep 2007EPA released the final report.
02-Feb 2019A clarification was made to text in the PPRTV assessment that describes the cancer weight-of-evidence descriptor for Pyrene.

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.