IRIS Toxicological Review of 1,4-Dioxane (Inhalation) (External Review Draft)
EPA has released the Toxicological Review of 1,4-Dioxane (Inhalation) (External Review Draft) for public review and comment. New studies regarding the toxicity of 1,4-dioxane through the inhalation route of exposure are available that were not included in the 1,4-dioxane assessment that was posted on the IRIS database in 2010.
[Update] EPA announced that an independent panel of experts will meet in Morrisville, NC on March 19, 2012 to discuss the draft report. [Federal Register Notice Feb 13, 2012]
EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of 1,4-Dioxane (inhalation) that when finalized will appear on the Integrated Risk Information System (IRIS) database. Please refer to IRISTrack - 1,4-Dioxane (inhalation) for the latest schedule updates.
|Aug 2010||EPA released the final assessment of 1,4-dioxane on the IRIS Web site.|
|May 2011||EPA initiated the interagency science consultation on the draft Toxicological Review of 1,4-Dioxane (Inhalation).|
|Aug 2011||EPA released the external review draft for public review and comment. EPA concurrently released the interagency science consultation draft toxicological review and charge, and interagency comments with EPA's response.|
|Sep 2011||EPA extended the close of the public comment period to November 15, 2011. [Federal Register Notice Sep16, 2011]|
|Feb 2012||EPA announced that an independent panel of experts will meet in Morrisville, NC on March 19, 2012 to discuss the draft report. [Federal Register Notice Feb 13, 2012]|
|May 2012||EPA released the comments from the public comment period and external review workshop.|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.