Inhibition of the Sodium-Iodide Symporter By Perchlorate: An Evaluation of Lifestage Sensitivity Using Physiologically Based Pharmacokinetic (PBPK) Modeling (External Review Draft)
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EPA first released this document in draft form as supporting material for the Preliminary Regulatory Determination on Perchlorate (FR Notice) in October 2008. The document has since been revised. The final report is available in response to comments from independent external peer review. A copy of the PBPK model code is available. In addition, the final peer review report and a summary of external peer review comments and EPA responses are available.
|Oct 2008||EPA released an external review draft for public review and comment as a supporting document to the EPA Drinking Water Ruling.|
|Dec 2008||EPA released the consolidated comments from the independent external peer review.|
|Aug 2009||EPA released the summary of external peer review comments and disposition for the 2008 external review draft of the report with the draft report.|
|Aug 2009||EPA publishes the final report.|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.