IRIS 2008 Agenda

Notice

[11/09] EPA is announcing the availability of literature searches for three IRIS assessments that were announced on the 2008 agenda (see new items in the substance list below) and is requesting scientific information on health effects that may result from exposure to these chemical substances. [Federal Register Nov 2, 2009]

[04/08] EPA announced the availability of literature searches for three IRIS Assessments that were announced on the 2008 agenda and requested scientific information on health effects that may result from exposure to these chemical substances. [Federal Register Apr 25, 2008]

[12/07] EPA released the IRIS 2008 agenda which contained a list of chemicals currently under assessment and a list of 20 candidates for upcoming IRIS assessments in a December 21, 2007 Federal Register Notice. EPA was soliciting scientific information from the public during the information gathering stage for the assessments listed in the agenda. Interested persons are invited to provide scientific analyses, studies, and other pertinent scientific information. Instructions for submitting information are given below.

IRIS 2008 Agenda: Literature Searches And Request For Information For New Starts

IRIS is an EPA database of human health effects that may result from exposure to chemical substances found in the environment. EPA's process for developing IRIS assessments is described in detail on the IRIS Process Web page.

Each year, EPA develops a priority list of chemicals and an annual agenda for the IRIS program and announces new assessments under review.

Starting this year, EPA is following a new process to actively solicit information from the public at the beginning of assessment development. As literature searches are completed for each chemical, the results will be available here (the available ones are listed in the table below). The public is invited to review the literature search results and submit additional information to EPA. Instructions for submitting information are given below. Based on the results of the literature searches and as EPA resources allow, assessments will be started for those chemicals with data that may support development of one or more toxicity values.

Substance	Literature Search Reports (Click PDF Links)	# Pages
Ammonia (CAS No. 7664-41-7)		33
Cyclohexane (CAS No. 110-82-7)		22
n-Heptane (CAS No. 142-82-5)		15
Hexavalent Chromium (Chromium VI ) (CAS No. 18540-29-9)		65
Methylcyclohexane (CAS No. 108-87-2)		10
2-Methylbutane (CAS No. 78-78-4)		4
2-Methylpentane (CAS No. 107-83-5)		6
3-Methylpentane (CAS No. 96-14-0)		6
n-Octane (CAS No. 111-65-9)		12
2,3,3-Trimethylpentane (CAS No. 560-21-4)		4
2,3,4-Trimethylpentane (CAS No. 565-75-3)		5
2,2,5-Trimethylhexane (CAS No. 3522-94-9)		4
Biphenyl (CAS No. 92-52-4)		55
Carbonyl Sulfide (CAS No. 463-58-1)		113
Diethyl Phthalate (CAS No. 84-66-2)		30
DiIsopropyl Ether (CAS No. 108-20-3)		8
Hexabromocyclododecane (CAS No. 3194-55-6, 25637-99-5, and 25495-98-1)		17
Manganese (CAS No. 7439-9)		373
N-Butanol (CAS No. 71-36-3)		12
Tertiary-Butanol (CAS No. 75-65-0)		39
Tertiary Amyl Methyl Ether (CAS No. 994-05-8)		21
Trimethylbenzene (1,2,4 and 1,3,5) (CAS No. 95-63-6 and 108-67-8 respectively)		25
Toxaphene (CAS No. 8001-35-2)		102
Tungsten and related compounds (CAS No. 7440-33-7) (Tungsten, Sodium Tungstate and Tungsten Trioxide)		18 7 2
Urea (CAS No. 57-13-6)		126

The public is also invited to submit information for any chemical currently undergoing assessment and for chemicals in the IRIS database (www.epa.gov/iris).

Additional Information