IRIS Toxicological Review of 1,2,3-Trichloropropane (External Review Draft)
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EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,2,3-trichloropropane (TCP) that once finalized will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization.
This assessment contains the derivation of a chronic reference dose and a chronic reference concentration, as well as a cancer characterization and the derivation of an oral slope factor.
|2003||EPA began reviewing the toxicological assessment of 1,2,3-trichloropropane.|
|Nov 2007||EPA released an External Review Draft for public comment and review.|
|Jan 2008||EPA announces the external peer review panel meeting in a Jan 18, 2008 Federal Register Notice.|
|Sep 2009||EPA released the Final Toxicological Review (PDF) (247 pp, 1.9M) and accompanying Summary for 1,2,3-Trichloropropane to the IRIS Web site.|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.